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SomaScan® Data Analysis

Get more value from your SomaLogic® SomaScan® data with expert, custom statistical analysis

* The images below come from running the Boulder BioConsulting analysis pipeline on the publicly available data kindly provided by SomaLogic on GitHub: https://github.com/SomaLogic/SomaLogic-Data)

 

  • Fast and accurate data analysis from raw ADAT files to final reports
  • Standard analyses include:
    • Normalization, quality control and outlier detection
    • Differential expression analysis
    • Multivariate and covariate analysis
    • Pathway enrichment
    • GSEA and DAVID analyses
  • Expert advise on best analysis approaches
  • Custom analyses and reports are our specialty

 

SomaLogic’s® SomaScan® technology uses a highly multiplexed detection system that combines protein-specific DNA aptamers with DNA sequencing technology to quantify the abundance of proteins in blood or other biological samples. SomaScan® has been used to identify biomarkers that are associated with specific diseases or conditions, to monitor disease progression, to develop new diagnostic tests, and to identify potential targets for drug development.

Our data analysis service includes data preprocessing, exploratory data analysis, statistical modeling, data visualization, and data interpretation. We provide comprehensive reports that summarize our findings and insights, and work with our clients to translate the results into actionable recommendations that can inform future research and development efforts.

To unlock the full potential of SomaScan®, you need robust statistical analyses to unravel the complex and voluminous data generated by the platform. Our team of experienced statisticians and data scientists has a deep understanding of SomaScan® technology and the complexities involved in analyzing large-scale proteomic data. We work closely with our clients to understand their specific research questions and goals, and tailor our analysis approach to meet their unique needs.

By choosing our SomaScan® data analysis service, you can gain a deeper understanding of the biological processes that underlie health and disease, identify potential biomarkers and therapeutic targets, and accelerate the development of new diagnostic and therapeutic interventions. Contact us today to learn more about how we can help you unlock the full potential of SomaScan® technology.

Publications

Several of our data analysis project have been incorporated onto published manuscripts in review. The first of these have been published now and the list of publications below will grow as additional manuscripts are released:

S. Vangeti, S. Falck-Jones, M. Yu, B. Österberg, S. Liu, M. Asghar, K. Sondén, C. Paterson, P. Whitley, J. Albert, N. Johansson, A. Färnert, A. Smed-Sörensen (2023) Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx eLife 12:e77345 (https://doi.org/10.7554/eLife.77345)

G. Tachas, C. Mueller, R. DeLisle, I. Woodcock, M. Ryan, A. Padhye, N. Desem (2023) ATL1102 treatment in non-ambulant boys with DMD modulates plasma proteins with roles in TGF-beta mediated fibrosis, and cartilage and bone physiology MDA Conference (link to poster)

S. Gupta, M.J. Westacott, D.G. Ayers, S.J. Weiss, P. Whitley, C. Mueller, D.C. Weaver, D.J. Schneider, A. Karimpour-Fard, L.E. Hunter, D.W. Drolet & J. Nebojsa Plasma proteome of growing tumors. Sci Rep 13, 12195 (2023). (https://doi.org/10.1038/s41598-023-38079-9)

The SomaLogic® logo and SomaScan® are trademark properties of SomaLogic, Inc.

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